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John Lehmann Ph.D. |
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Expert
Toxicology
Consultant /
Neurotoxicology / Pharmacology
Expert Witness |
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Areas of Toxicology Expertise:
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- Causation of Brain and Spine Injury and
Death, Respiratory Depression, Drug-Induced Memory Impairment
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Neurotoxicity, Biochemistry and
Neurochemistry of Stroke, Traumatic Brain Injury, Hypoxia-induced Brain
Damage, Neuro Toxicology, Neuropharmacology Consultant
- Design and Conduct of Clinical Trials,
Label Development
- Adequacy of Warning to Physician
Learned Intermediary in Medical Malpractice Issues
- Analysis of NDA, IND, PSUR, label
revisions, Investigators' Brochure, other FDA documentation
- Antiepileptics, Antidepressants
- Due Diligence by Liability Insurance
Carriers of Pharmaceutical Corporations
- Investment Analysis of Pharmaceutical
Corporations - Product Liability Risk Exposure
- Managed Care Patient Registry
Statistical Analysis (Pharmetrics Database, IMS Health Data)
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Description: |
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10 years experience as
Research Pharmacologist in
Pharmaceutical Industry in Drug Discovery in the United States &
France; 10 years Faculty in Medical School, Departments of
Psychiatry and Neurosurgery, PI of Clinical Trials;
Independent Toxicology Consultant
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Neuropharmacology Consultant
/ Pharmacology Consultant for 4 years. 20 years experience in
Neurotoxicology /
Neurotoxicity Research; Published over 60 peer-reviewed
papers. |
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Contact information |
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John Lehmann Ph.D.
Pharmikos Inc
PMB 311 - 303 W. Lancaster Avenue
Wayne PA 19087
Phone: 610 971 0611
Email:
Homepage:http://rtctox.com/lehmann.htm
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Professional Society
Membership: |
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Publications: |
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86
peer-reviewed papers and chapters available upon request. |
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Lehmann J, Arbilla S, Langer SZ.
Dopamine receptor mediated inhibition by
Pergolide [Permax] of electrically-evoked 3H-dopamine release from
striatal slices of cat and rat: slight effect of ascorbate.
Naunyn Schmiedebergs Arch Pharmacol. 1981 Aug;317(1):31-5 |
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Lehmann J, Langer SZ.
Muscarinic receptors on dopamine terminals in the cat caudate nucleus:
neuromodulation of [3H]dopamine release in vitro by endogenous
acetylcholine.
Brain Res. 1982 Sep 23;248(1):61-9. |
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Dictionary of Abbreviations and Acronyms used |
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Fda |
Food and Drug Administration
Fda Toxicology Consultant |
| Ind |
Investigational New Drug |
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| NDA |
New Drug Application |
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| Ntd |
NeuroToxicology Division |
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| Pi |
Principal Investigator |
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Psur |
Periodic Safety Update and Review |
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Sot |
Society of Toxicology
Expert Witness |
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Sas |
Statistical Analysis Software |
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